SCREENING ANTI-OXIDANT AND ANTI-TYROSINASE POTENTIAL OF PLANTS AND EARTHWORM EXTRACTS

Author(s): Usha Rani. J, Siva Prasad. B, Vutukuru. S.S., Kamala. G and Chand Pasha

Abstract: Plant and invertebrate animal such as earthworm extracts containing antityrosinase activity can be used as skin whitening agents. Application of such extracts in pharmaceutical and personal care products aids in protecting human skin from various diseases. Exploitation of these natural extracts for isolating antioxidant compounds and skin whitening agents is paramount. In this context, research pertaining to the antioxidant potential and tyrosinase inhibition of plant and earthworm extracts is gaining prominence. Moreover, reports inferring the occurrence of both antioxidant potential and tyrosinase inhibition in plant extracts such as flowers, herbs, vegetables, fruits, and earthworm are meager. Therefore, present study is intended to evaluate the total antioxidant potential thereby tyrosinase inhibition of plant and earthworm extracts by phosphomolybdate method. This study compared the total antioxidant potential and tyrosinase inhibition of plant extracts in flowers, vegetables, fruits. The results of the study revealed that extracts of flower- Rosa rugosa and fruits- Punica granatum Prunus armeniaca possess both antioxidant activity and anti-tyrosinase inhibition properties. Interestingly, earthworm extracts showed more antioxidant and antityrosinase activities when compared to plant extracts. Outcomes of the study assist in characterization of natural products including peptides that can serve as an antioxidant and anti-tyrosinase compounds. Thus, the study contributes to the existing knowledge on screening and identification of medicinally important peptides or compounds from plants and earthworm to treat skin disorders.

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