ANTIBACTERIAL ACTIVITY OF TRIBULUS TERRESTRIS L. AGAINST CLINICAL PATHOGENIC BACTERIA

Author(s): Umadevi V, Arjun N. Shetty and Srinath Rao

Abstract: The microbial infections are growing at an alarming rate. The discovery and exploration of antibiotic is a continuous process. There is an urgent need to curb the growing bacterial infections. Now a days the emerging antibiotic resistant strains are threat to mankind. The phytochemicals and secondary metabolites explored from plants have immense therapeutical and pharmaceutical properties. Tibullus terrestris is a member of family Zygophyllaceae. It is a low trailing prostrate annual herb. Each part of the plant is enriched with diverse phytochemicals and is a rich repository for phytochemicals such as Saponins and Flavonoids. These secondary molecules act against different gram positive and gram-negative bacteria. In the present study different solvent (Methanol, Chloroform and Hexane) extract of the plant was evaluated against different clinical isolates such as Pseudomonas aerogenes, Klebsiella sp. and Escherichia coli. Antibacterial activity of the plant was carried out by agar diffusion method and the same was determined by measuring the zone of inhibition (mm) according to the standard clinical parameters. In our study the methanolic extract (500 μg) of plant found to be effective against all the tested organisms.

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