ANTIOXIDANT AND ANTI-DIABETIC POTENTIAL OF MR-1 MULBERRY VARIETY

Author(s): Brijesh Ranjan, Pranab Lal Pakrasi and Venkatesh Kumar R

Abstract: The current study was aimed to analyze an antioxidant activity and anti-diabetic effect of mulberry leaf extract. Free radical quenching activity of MR-1 mulberry leaf was determined by in vitro and anti-diabetic activity of mulberry leaf extract was analyzed through in vivo using STZ diabetic male mice strain. The in vitro antioxidant studies revealed that the extract of MR-1 mulberry leaf exhibited highest antioxidant content (67.44 % in methanol solvent) and (73.45 % in ethanol solvent) at 400 μl concentration than ascorbic acid (62.37 % in methanol solvent) and (72.89 % in ethanol solvent) at 400 μl concentration. The MR-1 mulberry variety significantly (<0.05) decrease the glucose concentration and enzyme activity such as SGOT and SGPT, CAT, whereas the G-6PDH activity increases. The study revealed MR-1 mulberry variety has been potential for quenching of free radicals and capacity to reduce the blood glucose levels.

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