Study of Immunostimulatory Effect of Zingerone in Male Wistar Rats

Author(s): J. Juliet Poornamathy* and C. S. Parameswari

Abstract: Aims: Inflammation is a natural response of the mammalian body to a variety of hostile agents including parasites, pathogenic microorganisms, toxic chemical substances and physical damage to tissue. The present investigation is aimed to study the immunostimulatory effect of zingerone by analysing the various hematological and immunological parameters in male wistar rats. Methods: Thirty healthy rats were divided into five equal groups viz. Control (Group 1), administered food and water ad libitum, (Group 2), administered with olive oil (Group 3), administered with zingerone, (Group 4), administered with concanavallin, (Group 5), administered with Cyclosporin A(csA), followed by zingerone. Conclusion: It was observed that the zingerone treated rats succeed in persuading as effective compound in responding to both specific and non-specific immune response.

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