Evaluation of Phytochemicals and Validation of Antioxidant Potential of Wild solanum species from Mysore District, Karnataka, India (Research Article)

Author(s): M. Renu Priyadarshini and N. Lakshmidevi

Abstract: Solanum species are nutritional enriched group of plants recognized for high medicinal value in Angiosperm family. This diverse taxon comprises more than 2,300 species and great deal of studies support the economic importance of these species. However, limited studies have been done on the wild species. The intention of the study was to explore wild species of Solanaceae family for their antioxidant properties. Ten species growing in and around Mysore district, Karnataka, India were screened and phytochemicals from selected species viz Solanum seaforthianum, S. sisymbriifollium, S. diphyllum and S. anguivi were obtained by soxhlet extraction using methanol, chloroform, and water. Total reducing potential and four radical scavenging assays (DPPH, ABTS, H2O2 and NO) were performed and compared with total phenols and flavonoid content. Comparatively, aqueous extract of S. anguivi had high phenol (1.55 mg GAE/g) and flavonoid content (96.91 mg QE/g), consequently it displayed maximum reducing potential activity (64.09 mg AAE/g). Although concentration-dependent rise in the radical scavenging efficiency was detected in all species but significant variation (p<0.05) was noticed depending on the plant species and extraction solvent used. DPPH and H2O2 scavenging was higher in S. sisymbriifollium in methanol (97.98%) and chloroform extract (88.85%). S. diphyllum displayed more ABTS scavenging efficiency (86.21%) with EC50 value of 6.2 mg/ml and S. anguivi scavenged NO more efficiently with EC50 value of 7 mg/ml. Our findings support the ethno-pharmaceutical properties of selected plants and highlight their possible application in neutralizing free radicals and consequently managing oxidative stress related chronic diseases.

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