Lipid-Based Nanocarrier as Bioactive Transporter for Peptide Delivery: A Recent Update (Review Article)

Author(s): Suman Sah Kanu*, Abhimanyu Patel, Abhijeet Ojha, Saloni Jaswal, Praveen Chaudhary

Abstract: Lipid-based Nanocarriers are becoming popular nowadays because of their potential application in oral drug delivery systems having advantages like strong compatibility, and low toxicity. The bioactive molecules for nanocarrier drug delivery systems play a role in the promising treatment of diseases like urinary tract infection, dental problems, cancer, etc. To overcome the problem i.e., physical, and chemical unstability, various types of nanocarrier delivery systems that stabilize by using approaches of encapsulation technology are introduced. Lipid nanoparticles are stabilized by adding emulsifiers. The main aim of this article is a detailed discussion of different types of colloidal nanocarrier, advantages, disadvantages, different types of barriers to the delivery of protein and peptides, approaches for enhancing oral bioavailability of protein, and peptides. The eudratec pep technology, peptelligence and eligen technology are the newer technology to overcome the problem that arises in the protein and peptide delivery.

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