Catechin, as an Emerging Front-line Defense Flavonoid against Stress-Related Disorders: An Updated Review (Review Article)

Author(s): Vaishnavi M, Raksha B, Durga M*, Brindha Banu B and Deepikaa R

Abstract: Tea catechin is a class of flavonoids present in Camellia sinensis (green tea) and various other food sources synthesized by the Flavonoid pathway. It is known to have a wider range of biological activities, such as anti-inflammatory, anti-hyper lipidemic, anti-thrombogenic, anti-hypertensive, anti-ulcer, anti-oxidant, anti-proliferative and anticancer effects. Due to this wide range of properties, it has been used as an emerging front-line defence flavonoid against stress-related disorders. It is an effective flavonoid in the prevention and treatment of several stress-related diseases ranging from Obesity to Cancer, Diabetes to Neurodegenerative diseases, Urinary Tract Infections to Ulcers and Premenstrual Syndrome to Genetic disorders, Hypertension to Coronary Heart Disease and Brain aging. Thus, they have been used as a drug delivery system for the treatment of several stress-related diseases. It has been used as a nano encapsulated product, thereby increasing the medicinal values of green tea catechin. It is usually encapsulated with biopolymers to enhance its bioavailability, therapeutic efficiency and hydrophilicity. Catechin is being encapsulated by several methods such as Sonication and Ionic gelation etc. Antibiotics like Polyphenon 60 and Ciprofloxacin are derived from catechin and are used as intravaginal delivery treatment for curing Urinary Tract Infections. This review summarizes the properties of catechin that aid in the prevention of stress-related diseases and a brief view about polymeric nanoparticles.

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