INCIDENCE AND PREDOMINANCE OF DERMATOPHYTES AMONG THE PATIENTS WITH SUPERFICIAL SKIN INFECTION IN A TERTIARY CARE CENTRE IN BIRGUNJ

Author(s): Dipak Bhargava*, Suman Kumar Halder, Keshab Chandra Mondal, Sanjay Kar

Abstract: Dermatophytes are keratinophilic fungi, which causes the superficial mycotic manifestations known as dermatophytosis. The present work was intended to determine the predominance and antimycotic sensitivity pattern of dermatophytes among the patients. Clinical samples were collected from August, 2017 to May 2018, among the 230 patients presenting characteristic lesions of dermatophytosis. Clinical specimens collected were processed by means of potassium hydroxide wet mount, culture and the biochemical tests to identify the dermatophytes. In this present work antimycotic sensitivity testing by the disc diffusion method was also conducted. Of 230 clinical samples, the maximum number of dermatophytosis was in the age group of 31-40 years. Out of the 230 clinical samples, 47.3% were positive in the potassium hydroxide wet mount and a sum of 53.9% was positive for the dermatophytic growth in culture. Frequency of Tinea corporis association is significantly higher than Tinea cruris (p < 0.05) and Trichophyton rubrum was the predominant etiological agent with 53.2% of the isolates. Antimycotic susceptibility test of the isolated Dermatophytes shows maximum susceptiblity against itraconazole (10mcg) and miconazole (30mcg), whereas least susceptible towards fluconazole (10mcg) and ketoconazole (50mcg). Systemic surveillance of antifungal susceptibility test should be carried out to resolve the optimal treatment regimen.

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