Volume 8, Issue 3, July 2018
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DEVELOPMENT AND IN VITRO CHARACTERIZATION OF ACETOHYDROXAMIC ACID FLOATING MICROBALLOONS
Author(s): Munija Pancheddula and Shayeda*
Abstract: In the present work, floating microballoons of Acetohydroxamic acid using Eudragit RS 100, Eudragit S 100, HPMC
K4M, Ethylcellulose as polymers were formulated to deliver Acetohydroxamic acid via oral route. The results of
this investigation indicate that, solvent evaporation method can be successfully employed to formulate
Acetohydroxamic acid microballoons. The in-vitro release studies demonstrated that microballoons of
Acetohydroxamic acid prepared using Eudragit RS 100 along with Eudragit S 100 in 1:1 ratio (formulation F5)
shown maximum amount of drug release, hence it is considered as the optimized formulation. The in vitro release
kinetics revealed that the optimized formulation (AHF5) release the drug in zero order manner based on the
regression values of kinetic models.
PAGES: 698-709 | 41 VIEWS 43 DOWNLOADS
How To Cite this Article:
Munija Pancheddula and Shayeda*. DEVELOPMENT AND IN VITRO CHARACTERIZATION OF ACETOHYDROXAMIC ACID FLOATING MICROBALLOONS. 2018; 8(3): 698-709.