ISOLATION, PURIFICATION AND CHARACTERIZATION OF THE GUM EXUDATES FROM MARDI (TERMINALIA TOMENTOSA)
Author(s): Mangesh M. Kumare and Giridhar R. Shendarkar
Abstract: Mardi (Terminalia tomentosa) is Important gum producing tree of Gadchiroli district and having considerable, commercial and industrial importance therefore the study undertaken for isolation of gum exudates obtained from Mardi and their characterization and evaluation. The Gum was dried, pulverized and drawn out using distilled water and isolated by acetone. Various physicochemical tests and other parameters like micromeritic properties, swelling index and viscosity were evaluated for characterizing the isolated and purified gum. The result revealed that water-based extraction of gum has excellent flow properties. It has a good swelling index of 44 ± 0.58%. The gum was examined for purity by carrying out various phytochemical tests and showed that carbohydrates, sugar and amino acids and gum were found to be present. The pH of 1% solution of gum was found to be 5.6 ± 0.01 and the total ash value was found to be 3.20 ± 0.01. Bulk density, tapped densities were found to be 0.73 ± 0.01 g/cm3 and 0.91 ± 0.01 g/cm3, respectively. Bulkiness was found to be 1.37 ± 0.02 cm3/g. Hausner’s ratio and carr’s index were found to be 1.25 ± 0.01 and 19.78 ± 0.12%. Extracted gum wasswells and forms a gel with cold water, form a viscous colloidal solution in hot water and this property can be utilized for sustained drug delivery. The results of evaluated parameters showed that mardi gum has satisfactory pH and physicochemical properties, which can be used as pharmaceutical adjuvant in formulating various dosage forms.
PAGES: 107-112 | 130 VIEWS 73 DOWNLOADS
How To Cite this Article:
Mangesh M. Kumare and Giridhar R. Shendarkar. ISOLATION, PURIFICATION AND CHARACTERIZATION OF THE GUM EXUDATES FROM MARDI (TERMINALIA TOMENTOSA). 2018; : 107-112.