PHYTOCHEMICAL SCREENING, ANTIFUNGAL AND ANTIOXIDANT ACTIVITY OF STROBILANTHES HEYNEANA NEES (ACANTHACEAE)

Author(s): Arbin Ayesha, Dhaya Shree V.S, Sahana B.K, Saema Noorain G.K and Prashith Kekuda T.R*

Abstract: Objectives: The present study was carried out to evaluate antifungal and antioxidant activity of leaf extract of Strobilanthes heyneana Nees. (Acanthaceae). Methods: The shade dried, and powdered leaf material was extracted by maceration technique using methanol. Antifungal activity was determined by poisoned food technique against two seed-borne fungi. Antioxidant activity was evaluated by DPPH free radical scavenging and Ferric reducing assays. Results: Preliminary phytochemical analysis revealed the detection of alkaloids, flavonoids, tannins, saponins, sterols and triterpenoids. Extent of reduction of mycelial growth of Aspergillus niger and Bipolaris sp. by leaf extract was found to be >50%. Extract was shown to exhibit marked dose dependent radical scavenging and ferric reducing potential. Conclusions: Leaf extract of S. heyneana was promising in terms of antifungal and antioxidant potential. Further studies are to be undertaken to isolate active principles from the leaves and to investigate their biological activities.

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