IN VITRO ANTI-INFLAMMATORY ACTIVITY OF THE STEM BARK OF Nyctanthes arbor-tristis (L.)

Author(s): Vijayalakshmi S and Ananthi T*

Abstract: Nyctanthes arbor-tristis is popularly known as Night jasmine used extensively in the Ayurvedic system of medicine. To evaluate the anti-inflammatory potential of ethanolic bark extract of Nyctanthes arbor-tristis. Preliminary phytochemical analysis showed the presence of alkaloids, flavonoids, glycosides, tannin. Different concentrations viz 50, 100, 200, 400 and 800 μg/ml. Nyctanthes arbor-tristis were used to study the in vitro anti-inflammatory activities albumin denaturation and HRBC membrane stabilization activity. Aspirin was used as reference drug. It was found that ethanolic bark extract of Nyctanthes arbor-tristis was dose dependent RBC membrane stabilization and protein denaturation activity. The results suggested that anti-inflammatory activity of Nyctanthes arbor-tristis was reasonably due to the presence of flavonoid, quercetin. So, it can be used as a potential source of anti-inflammatory agent.

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