Phytochemical Analysis and Biomedical Applications of Ipomoea pescaprae Flower Extract-An In Vitro Study

Author(s): Nightingale Sheeba, S, Vinoliya Josephine Mary, J*, Mary Mettilda Bai, S and Jilian V. Paul

Abstract: Traditional remedies have a long-standing history in India and continue to provide very useful and applicable tools for treating various ailments. Ipomoea pes-caprae /Ipomoea biloba commonly known as morning glory which is found along the sea shore belongs to the family Convolvulaceae. Phytochemical analysis revealed the presence of protein, saponin, tannin, glycosides, alkaloid and flavonoid as the major components in the flower extract of Ipomoea pes-caprae. Aqueous extract of the fresh flower was evaluated for its antibacterial potential against Gram +ve and Gram –ve bacteria such as Staphylococcus aureus, Bacillus subtilis, Streptococcus mutans, Lactobacillus sp., Proteus vulgaris, Klebsiella pneumoniae, Escherichia coli and Proteus mirabilis. The aqueous extract inhibited most of the selected bacteria except Klebsiella pneumoniae. The anticancer activities of the flower of Ipomoea pes-caprae were evaluated against cell lines A549, HT29 and MCF7. High cytotoxic effect was observed against A549 cell line. Our results suggest that flower extracts are promising therapeutic agents that can target specific bacteria and cancer cells.

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