Investigation of Anti-Inflammatory Activity of Aqueous and Ethanolic Extract Diplocyclos Palmatus (L.) Jeffry. in Experimental Animals

Author(s): Paras Gupta*, Ravindra Singh and R.D. Wagh

Abstract: Diplocyclos palmatus (L.) Jeffry. (H: Shivlingi; Family: Cucurbitaceae) had been widely used for its reported biological activities in indigenous system of medicine. The present investigation was carried out to access the effect of aqueous and ethanolic extract of stem and leaves of Diplocyclos palmatus (L.) Jeffry. For its anti-inflammatory activity. The anti-inflammatory activity was evaluated using acute inflammatory models viz., carrageenan induced paw oedema. Oral administration of the extract at the doses 100 and 200 mg/kg b.w. exhibited dose dependent and significant anti-inflammatory activity in (p < 0.01).

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