In Vitro Antidiabetic and Hypolipidemic Activity of Selected Medicinal Plants

Author(s): Anjana Rani, Sunil Kumar* and Roop K Khar

Abstract: Diabetes mellitus is one among the fundamental ailments prevailing around the world. New helpful methodologies are being researched to direct postprandial glucose levels because of serious symptoms of commercially available anti-diabetic drugs. Alpha-amylase and glucosidase are responsible for postprandial glucose levels in this manner, distinctive plant extracts with alpha-amylase and glucosidase inhibitory action are being explored that may diminish postprandial blood glucose levels, hence being an intriguing and novel remedial focus for diabetes mellitus treatment. Hindrance of gastrointestinal starch and lipid digesting enzymes has been mainstream methodologies to tackle with the diabetes. In the present investigation we have assessed in-vitro α-amylase, α-glucosidase, DPP4 and pancreatic lipase inhibition potential of some plants.

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