IN VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY OF THE FLOWER EXTRACTS OF PEDALIUM MUREX L.

Author(s): D. Prabhakaran*, A. Rajeshkanna and M. M. Senthamilselvi

Abstract: To evaluate the antioxidant and anti-inflammatory activities of the solid powder obtained from the ethyl acetate fraction from the flower Pedalium murex L. The flower extract was evaluated for antioxidant activity by 1,1–diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay and reducing power assay was carried out by FRC (Ferric Reducing Capacity) assay method. The in vitro anti-inflammatory activity was evaluated using human peripheral blood mononuclear cells (PBMC) were stimulated by lipopolysaccharide (LPS) to evaluate nitric oxide (NO) production method. The solid powder obtained from the ethyl acetate fraction from the flower Pedalium murex L showed a good antioxidant activity in scavenging DPPH radical and FRC assay with compared standard sample. This solid powder also showed good anti-inflammatory activity in cell viability (LPS induced PBMCs) assay and nitric oxide (NO) assay. These results suggest that the solid powder obtained from the ethyl acetate fraction from the flower Pedalium murex L have significant antioxidant and anti-inflammatory activities.

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