EVALUATION FOR ANTI OXIDANT ACTIVITY OF PLANTAGO ASIAATICA EXTRACTS

Author(s): Mohammad Zubair Shareef, *Gummadi Sridhar Babu and P. S. Malathy

Abstract: Plantago Asiatica has antioxidant activity against Azathioprine induced oxidative stress in rats by decreasing the oxidative stress biomarkers serum creatinine, serum urea in kidneys. Plantago Asiatica has antioxidant effect, elevated by measuring antioxidant enzymes. There is increase in superoxide dismutase in liver and kidney tissues in Azathioprine induced oxidative stress in rats. Plantago Asiatica has high scavenging activity against DPPH free radical generating system. Plantago Asiatica has nephropretective effect against Azathioprine induced toxicity in kidneys by observing the histopathological changes in rat kidney tissues. Plantago Asiatica has many pharmacological activities like anticancer, antimicrobial, anti-inflammatory, analgesic, antiarthritic, antibacterial, anti-HIV, and antihelmntic activities.

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