In-Vitro Antioxidant Potentials and Free Radicals Scavenging Activity of Solanum Incanum L.

Author(s): Kaliyamoorthy Kumar and Kathiresan Sivakumar*

Abstract: In recent trends in biomedical technology consist of growing clinical demands researcher to searching for new suitable therapeutic compound to direct towards to utilize of Biodiversity. However, the present scenario plant-based antioxidant can be effectively replacing the modern medicine. Although, Solanum incanum L., is roadside weed shrub and its ripened berries were treating throat like sore throat, angina, stomach-ache, painful menstruation, liver pain, pneumonia and rheumatism. In the present investigation carried out the antioxidant potentials of Solanum incanum for their free radical – scavenging activities was evaluated by Hexane, Chloroform, Ethyl acetate and methanol extracts by terms of DPPH free radical scavenging activity, Hydroxyl radical (OH•) – scavenging activity, Total Antioxidant activity. The estimation of crude extracts (Conc. 50, 150,250 and 500 μg/ml) by the IC50 value were calculated, compare to standard antioxidant for L-Ascorbic acid. All above mentioned the solvent extracts were analysed and result were concluded that the Hexane extract shows maximum free radical scavenging potentials compare the standards L-Ascorbic acid. However, total Phenol content (8.75±0.38mg/ml) Gallic acid equivalent (GAE), Total Flavanoid content (10.36±0.55mg/ml) Quercetin (QE) equivalent were found higher in Hexane extracts. In the present investigation revealed that S.incanum can be a valuable source of natural antioxidants with their potential utilization in different fields of biomedical industrial application.

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