Toxicity Effect on Biochemical and Stress Markers Alterations in Liver and Kidney from Cadmium Nanoparticles Exposed Fish, Catla catla

Author(s): Nithya. B, Sangeetha .S and Deepa Rani .S*

Abstract: Nanometal contamination in the ecosystem is proven by previous research studies. Nanometal persistence and toxicity is differed from heavy metal toxicity. In the present study, cadmium nanoparticles (CdNP) were exposed to Catla catla and subsequently the biochemical changes in the fish were recorded. Acute lethal toxicity (LC50) of cadmium nanoparticle to Catla catla fish was determined as 50ppm. The fishes were exposed to sublethal concentration of 20ppm of cadmium nanoparticles for 15 days continuously and the biochemical parameters such as protein, carbohydrate and lipids were estimated. The total carbohydrate, protein and lipids in liver and kidney were decreased in their level after exposing the cadmium nanoparticles. Moreover, the level of antioxidant enzymes such as catalase and superoxide dismutase in liver and kidney were increased at beginning days of CdNP exposure and significantly reduced after 10 days of cadmiuim nanoparticle exposure. Metabolic enzymes aspertate aminotransferase, alanine aminotransferase, lactate dehydrogenase and malate dehydrogenase were significantly decreased when compared to control. The present study clearly demonstrated the biochemical alteration upon cadmium nanoparticles exposure in Catla catla.

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