A Review on Stem Cells Therapy- A New Treatment for Cerebral Palsy

Author(s): V.S.R.S. Bramarambica Devi. Konatham*, Nagaraja.Jarugula, M. Prasada Rao, Lakshmi Kousalya. Chirumamilla

Abstract: Cerebral palsy is a neurological disorder caused by non-progressive brain injury (or)malformation that occurs during perinatal stage. CP is caused by many factors like premature birth infection in uterus, lack of Nutrional support during development, lack of oxygen at the time of birth and genetic abnormalities. It affects muscle movement and coordination. Main symptoms-visual and cognitive impairment. Stem cells are the precursors for any cells. These are unspecialized cells which becomes specialized cells such as brain cells, heart cells and muscle cells. Stem cell transplantation is a regenerative therapy that has the potential to replace the damaged cells and non-functional cells in the brain of CP patients. From the clinical trials phase II data, it suggests that it’s beneficial in the patient with acute CP when compared to chronic CP patients. Far more research is needed to determine the appropriateness of this therapy.

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