Extraction and Identification of Bioactive Compounds from Marine Bacteria Pseudoalteromonas tunicata through FTIR, GC-MS and NMR Studies

Author(s): P. N. Rajarajan*, P. Jeganathan , K. Rajeswari, N. Sumathy and A. Uma Devi

Abstract: Natural products are of special interest because of the dazzling diversity and uniqueness of the creatures that make the sea their home. One reason marine organisms are so interesting to scientists is because in adapting to the various ocean environments, they have evolved fascinating repertoires of unique chemicals to help them survive. Interestingly, more than 120 drugs available today derive from land-based microbes. But, scientists see marine-based microbes as the most promising source of novel medicines from the sea. In all, more than 20,000 biochemical compounds have been isolated from sea creatures since the 1980s. In this study, over all 3 secondary metabolites / bioactive compounds were extracted from marine bacterial strains Pseudoalteromonas tunicata. The Pseudoalteromonas tunicata secrete 3 different bioactive compounds (Salicylic acid, Isatin and Ethyl vinyl sulfone) in the lab-scale fermentation broth. The bioactive compounds were screened by various methods such as Gas Chromatography – Mass Spectroscopy (GC-MS), Fourier Infra-Red Spectroscopy (FT-IR) and Nuclear Magnetic Resonance (NMR) spectrum activity.

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