Synthesis of Silver Nanoparticles and Phytochemical Analysis of Benincasa hispida Peel Extract

Author(s): Yadav Shweta S, Kalbhor Shweta D, Waghmode Meghmala S and Patil Neha N*

Abstract: Benincasa hispida is a member of family cucurbitaceae it has nutritional and medicinal properties. Benincasa hispida is considered as one of the sacred fruit in India. This fruit found to have wide applications. Current research was carried out on the evaluation of in vitro activities and silver nanoparticle synthesis of Benincasa hispida peel extract. The phytoconstituents of Benincasa hispida fruit peel includes alkaloids, steroids, resin and vitamins. Benincasa hispida fruit peel gives red florescence at 365nm (under long UV) in Benzene, Diethyl ether, Chloroform, Ethanol and acetone. Proximate analysis which includes ash value, moisture content, extractive values, total solid content and crude fiber content of fruit peel powder was determined. The pharmacological activities such as anti-arthritic, thrombolytic, anti-oxidant, anti-diabetic showed high economic value of fruit peel. The extract was found to have antifungal activity against Trichophyton spp., fungi responsible for athlete’s foot infection. Herbal soap was prepared using Benincasa hispida peel extract found to be effective for the treatment of athlete’s foot infection. Green synthesis of silver nanoparticles using peel extract of Benincasa hispida is a rapid and ecofriendly method. The characterization of silver nanoparticles, was done using FTIR, SEM, XRD, and UV-Visible spectrophotometer. The silver nanoparticles found to have maximum absorbance at 350nm and the size of nanoparticles found to be in the range 28-38nm with irregular shape. Antifungal activity against Trichophyton sp. (Causing Athletes foot infection) showed by silver nanoparticles. The H2O2 detecting ability of silver nanoparticles was found.

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