Structural Elucidation and Efficacy Comparison of Crude Powder of Selected Brown Seaweed and Isolated Sulphated Polysaccharide Towards Anti-Inflammation by Protein Denaturation Method

Author(s): S. Deepa*, D. Velmurugan, K. Sujatha and K. Sathesh Kumar

Abstract: Brown algae consists of Fucoidan, a sulphated polysaccharide as its main constituents especially in its extracellular matrix. It has various biological activities, like immunomodulatory, anti- tumour, anti-inflammatory, anti-coagulant, etc. Prescribed methods based on the reference articles were followed for Extraction followed by Purification of Fucoidan from Turbinaria ornate. This study is to determine the anti-inflammatory potency of the isolated fucoidan from the selected brown seaweed, after proper purification and characterization using IR, NMR and GC-MS collected from Mandabam area, Ramanathapuram District and compared with that of the crude powder of the same selected seaweed. The results revealed that the isolated and purified Fucoidan has potential anti-inflammatory activity than the crude T.ornate powder using protein denaturation method.

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