A Comparative Study of Thyroid Hormone Levels in Severe and Mild Pre-Eclmaptic Women and Normal Pregnant Women

Author(s): B. Prashanthi*, Himaja, Joseph and Jagan

Abstract: Pregnancy is usually associated with many complications; one among them is pre-eclampsia which is major cause for the maternal and perinatal morbidity and mortality. The present study deals with the comparison of the thyroid hormone levels in the pre-eclamptic patients (severe& mild) and normal pregnant women. The main objective of this study is to prevent the intra uterine deaths of foetus, preterm labour and to have a matured full-term delivery. This is a case- control, prospective interventional study designed to compare the thyroid hormone levels with pre-eclamptic patient and normal pregnant women. Levels of T3, T4 in pre eclamptic women (cases) were significantly lower and TSH is significantly higher when compared to the normal pregnant women (controls). Primary hypo-functioning of the thyroid can accompany mild preeclampsia and possibly contribute to the pathogenesis. Identification of thyroid abnormalities and appropriate measures might affect the occurrence and severity of morbidity and mortality associating with pre-eclampsia.

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