Prescribing Pattern of Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) In Orthopedic Patients

Author(s): Chinju Anil, Dan Monsy, Mohamed Thayub, Pandala Sreenivasula Reddy and Leena Pavitha P*

Abstract: Aim: The aim of the study is to evaluate Prescribing pattern of NSAIDs which includes Prevalence, Indication and Categories of drug used in a Tertiary Care Hospital and Community clinical care set up. Methodology: An Observational Study was carried out over a period of 6 months. A total of 203 Prescription were collected, documented and analyzed in OPD and total of 256 Prescriptions was collected and analyzed in the community clinical setup. The Rationality of the prescriptions was evaluated using WHO core indicators 2017, NLEM 2015 and DU90%. Drug consumption by the patients was calculated using DDD/1000/day and the patient under the risk of developing ADR was assessed using 299FM.4 guidelines by NHS. The Pattern of the drug prescribing was assessed using WHO core indicators 2017. Results: Of the 203 cases. The most encountered NSAID was Paracetamol 62.75% among the class of NSAIDs used Non-Selective COX inhibitors 32.15% were more preferred over selective COX 2 inhibitors 5.10% Only 21% drugs were prescribed by generic name, compliance with the NLEM was found to be 59.94%. Five out of nine drugs constitute to DU90% and Risk factors of the drugs were assessed. Of 256 prescriptions analyzed in the OPD Ketorolac 97 (65.99%) was the preferred drug of choice, Non-Selective COX inhibitors was more preferred. Only 1.20% drugs were prescribed by generic name, compliance with the NLEM was found to be 5.02%. Conclusion: In the present study showed that Paracetamol was used commonly for the indications of fracture and arthritic conditions in IPD. Ketorolac was used for short term therapy of pain and inflammation in OPD. Nonselective COX inhibitors more preferred over COX 2 inhibitors.

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