Evaluation of Antioxidant Activity of Solanum melongena Fruit Peel Extract

Author(s): J. Sarkar*, A. Garg and P. Gupta

Abstract: Aim:This study was planned to evaluate in-vitro anti-oxidant activity of Solanum melongena purple coloured fruit peel hydro-alcoholic extract (PHAE). Methods: Antioxidant activity of Solanum melongena purple coloured fruit peel hydro-alcoholic extract (PHAE) was first subjected to preliminary phytochemical screening and then various in-vitro anti-oxidant studies were conducted namely; 1,1-Diphenyl-2-picrylhydrazyl (DPPH) Scavenging activity, Hydrogen Peroxide (H2O2) Scavenging activity, Nitric Oxide (NO) Scavenging activity, Superoxide (O−2) Scavenging activity, Total Reducing-Power assay (TRP) and Total Phenol content (TPC). Results: The percent (%) inhibition against DPPH radical, H2O2 radical, NO radical, O−2 radical by PHAE was found to be 62.17, 64, 69.65, 74.77 respectively. Effective Concentration (EC50) in TRP assay was found to be 59.31 μg/ml for PHAE. TPC was found to be 782 mg of gallic acid equivalent per gram of PHAE. Conclusion: Under the testing conditions, the results from these in-vitro antioxidant tests evince that PHAE has significantly high antioxidant activity. So, this merits further investigation for hepatoprotective activity in-vivo/ humans too.

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