Liposomes-A Novel Drug Delivery System: A Review

Author(s): Sunitha Reddy M* and Amulya Etikala

Abstract: Novel drug delivery systems play a major role in providing an optimum dose at a right time and to the right location. Liposomes are the novel drug delivery systems consisting of an aqueous compartment enclosed by means of one or more phospholipid bilayers. Liposomes are the most successful drug delivery systems which uses nanotechnology to potentiate therapeutic efficacy and reduces the toxicities that occurs due to conventional medicines. The ability of liposomes to encapsulate both hydrophilic and lipophilic drugs have allowed these vesicles to become useful drug delivery systems. The present article gives an idea regarding the classification of liposomes, mechanism of vesicle formation, advantages, disadvantages, methods of preparation of liposomes, novel liposomes, applications and marketed products.

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