PHARMACOLOGICAL EVALUATION OF POLYHERBAL EXTRACTS OF Amorphophallus paeoniifolius, Citrus sinensis AND Plumbago zeylantia FOR ANTI FUNGAL ACTIVITY

Author(s): Matangi Suryaprabha* and Nadendla Rama Rao

Abstract: Fungal infections may take the form of superficial infections involving the skin or mucous membranes or systemic involving various internal organs. Deep infections are systemically treated with drug therapy. Among the fungi that cause systemic infections are Aspergillus spp., Nocardia asteroides , Histoplasma capsulatum and Coccidiodes immitis. Among ancient civilizations, India has been known to be rich repository of medicinal plants. Recently, WHO estimated that 80 percent of people worldwide rely on herbal medicines for some aspect of their primary health care needs. Treatment with medicinal plants is considered very safe and there is no or minimal side effects. Medicinal plants are considered as rich sources of ingredients which can be used in drug development. The Ayurvedic literature Sarangdhar Samhita’ highlighted the concept of polyherbalism to achieve greater therapeutic efficacy. The active phytochemical constituents of individual plants are insufficient to achieve the desirable therapeutic effects. When combining the multiple herbs in a particular ratio, it will give a better therapeutic effect and reduce the toxicity. This research mainly focuses on important of the polyherbalism and its clinical significance.

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