Pharmacological Evaluation of Polyherbal Extracts of Amorphophallus paeoniifolius, Citrus sinensis and Plumbago zeylantia for Anti-Microbial and Anthelmintic Activity

Author(s): Matangi Suryaprabha* and Nadendla Rama Rao

Abstract: Recently there has been a lot of attention focused on producing medicines and products that are natural. Antibiotics provide the main basis for the therapy of microbial (bacterial and fungal) infections. Since the discovery of these antibiotics and their uses as chemotherapeutic agents would lead to the eventual eradication of infectious diseases. However, overuse of antibiotics has become the major factor for the emergence and dissemination of multi-drug resistant strains of several species of microorganisms. The worldwide emergence of Escherichia coli, Klebsiella pneumoniae, Haemophilus and many other ß-lactamase producers has become a major therapeutic problem. Multi-drug resistant strains of E. coli and K. pneumoniae are widely distributed in hospitals and are increasingly being isolated from community acquired infections. Medicinal plants are abundant source of antimicrobial molecules. A wide range of medicinal plants extracts are used to treat several infections as they have potential antimicrobial activity. Some of these bioactive molecules are screened and traded in market as raw material for many herbal industries. This research suggests the aid of polyherbal combination of Amorphophallus Paeoniifolius, Citrus Sinensis and Plumbago Zeylantia which may enhance the potency of the medicinal plants even in case when they use alone individually.

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