Synthesis and Evaluation of Benzofuran Derivatives for Antibacterial Activity

Author(s): T. Surakshitha*, A. Raghuram Rao, Ch. Pragna, P. Rani, Ch. Sampoorna and A. Manasa

Abstract: Infectious microbial diseases remain pressing problems worldwide, because resistance to a number of antimicrobial agents among variety of clinically significant species of microorganisms, like Methicillin-Resistant Staphylococcus aureus (MRSA) has become an important global health problem. Hence, furan derivatives have been widely used as antimicrobial agents. Prompted by these observations and as part of synthetic effort directed towards the synthesis of antimicrobial agents, various new substituted furans are being synthesized and evaluated. It is one of the most important classes of fused ring heterocyclic compounds. The benzofuran derivatives are naturally occurring and possess many biological applications. Numerous synthesized benzofuran derivatives were found to be biologically active. Now-adays many synthetic benzofurans are used as good inhibitor, antimicrobial, anti-inflammatory, antibacterial, antiviral, antioxidant, antitumour, antiproliferative and antialzheimer.

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