Biologically Fabricated Silver Nanoparticles from Mesophilic Bacteria (E. coli) Produces Cytotoxicity Through Apoptotic Signaling in Breast Cancer MCF-7 Cells (Research Article)

Author(s): Thirumalpur Neelakandan Baskaran, Murali Santhosh, Kalaimani Saravanan, Sivaji Sathiyaraj, Gunasekaran Suriyakala, Babujanarthanam Ranganathan*

Abstract: The most exclusive properties of silver nanoparticles are very small with optical frequency when the propagation of surface-plasmon, non-toxic with significant electro-thermal conductivity. Moreover, it has been exhibiting several broad spectra of highly resistant antimicrobial activity and anticancer properties. There are various methodologies have been adopted to synthesis the AgNPs which includes electrochemical, microwave, chemical reduction, biochemical, ultra-sonication. This method implies highest energy consumption, usage of chemical may produce toxicity and highly hazardous. Therefore, use of simple and low-cost methodology with bio-compatible are considered crucial approach for synthesis of AgNPs.

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