Larvicidal Potential of Padina gymnospora and Sargassum swartzii Methanolic Extracts Against Dengue Fever Mosquito, Aedes aegypti (Linnaeus) (Diptera: Culicidae) (Research Article)

Author(s): M. Muthu Sheeba, G. Adaikala Raj*, C. Justin David, M. Arivalagan and P. Gnana surya

Abstract: Dengue hemorrhagic fever causes 2 million infections, 500,000 illnesses, and 12,000 deaths. According to a recent report, more than 50 million people are at risk of contracting dengue fever around the world. Mosquito vectors transmit diseases such as dengue fever, yellow fever, zika, chikungunya, filariasis, onchocerciasis, and mansonellosis. The present study was designed to evaluate the larvicidal potential of different concentrations of methanolic extracts of Padina gymnospora and Sargassum swartzii. The larvicidal potential of the selected brown seaweed extracts were determined against 4th instar larvae of Aedes aegypti using various concentrations viz., 200, 400, 600, 800 and 1000 ppm. The mortality counts were made after 12h, 24h and 48h of incubation and LC50 values were calculated. The highest larvicidal activity against A. aegypti was [LC50 =621.5 and LC90 = 1639.0 ppm (After 12h); LC50 =819.8 and LC90 = 1448.1 ppm (After 24h) and LC50 =621.5 and LC90 =1213.1 ppm (After 48h)]. The phytochemical analysis of methanolic extracts of P. gymnospora and S. swartzii showed the presence of terpenoids, tannins, phenolic compounds, and steroids. The efficacy of the extracts of P. gymnospora and S. swartzii may be attributed to the phytochemicals present in the methanolic solvent extract. Further investigations are underway to elucidate novel compounds with mosquito repellent activity from the extracts.

PAGES: 212-217  |  112 VIEWS  98 DOWNLOADS