A Brief Review on Formulation and Evaluation of Ethosomal Gel for Arthritis with Herbal Extracts (Review Article)

Author(s): Nabamita Basu*, Narasimha Buragommula, Hephzibha B, Jagadeesh Induru2

Abstract: The aim of this article is to gather information about Rheumatoid Arthritis (RA) and its consequences for various uses in medical field with herbal formulation mainly plants extracts. Now a days phytoconstituents from many plants are tremendously used in combination with chemical constituents to decrease its adverse effects and contraindications. Ethosomes drug delivery is one of the most challenging works in research to improve the skin penetration capacity of various drugs. The rate of absorption is high while promoting the drug through this delivery system. Much research is going on to improve the systemic aabsorption of drug through trans-dermal drug delivery system. Various plants extracts are also incorporated in ethosomal vehicle system to treat many types of disorders like Rheumatoid arthritis using gel formulation. Oral drug delivery causes lots of adverse effects and contraindications, hence, to reduce these, a mode of drug delivery by topical administration is effective in treating many disorders. Several plant’s secondary metabolites are also playing vital role in curing many disorders and no side effects have been reported. Novel modified lipid carriers as ethosomes which have been suggested to have improved vesicular properties and skin penetration capacity.

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