Development of Palatable Formulation of Antidiabetic Drug (Research Article)

Author(s): R. A. Mahalle, M. U. Bhoir, P. R. Bhosale, P. V. Chaudhari, V. N. Chauhan, N. S. Chogale, A. Jain

Abstract: Aim: The objective is to develop palatable formulation by masking bitter taste of anti-diabetic drug. Method: In the current report advancement of natural chocolate by utilizing Withania coagulans was done. By utilizing fruits of Withania coagulans, lab made chocolates was ready and assessed for outward presentation, aspect, hardness, blooming test. Mobile phase for thin layer chromatography was developed using ethanol: water (5:5). Result: chocolate formulation provides a palatable means for delivering medicaments through oral delivery. The formulation provides sweetening property as compare to others, pH & stability profile to be satisfactory. Conclusion: From this study we can conclude that withanolides may be present in the extract which may be confirmed if future by isolation of components present in the extract.

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