In Vitro Antiurolithiatic Activity by Inhibition of Calcium Oxalate Crystallization of Methanol Extract of Imperata Cylindrica L (Research Article)

Author(s): Susmita Roy*, Lakshmi Kanta Kanthal, Suman Pattanayak, Tanmoy Payra, Sushovan Dey

Abstract: Aim: The study investigates the in vitro antiurolithiatic potential of the methanolic extract of the whole Imperata cylindrica L. plant through its inhibitory effect on calcium oxalate crystallization. Methods: Antiurolithiatic activity was evaluated using a nucleation assay to test the extract’s inhibitory effects on urolithiasis at concentrations ranging from 100 to 800 μg/mL. A standard antiurolithiatic drug, Cistone, was used as a reference. Phytochemical analysis revealed the presence of amino acids, proteins, carbohydrates, saponins, phenols, and flavonoids, while alkaloids and glycosides were not detected.

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